Clinical features of mastocytosis at pediatric patients

Abstract

Mastocytosis is relevant to heterogeneous disease group characterized with redundant accumulation and proliferation of mast cells in tissues. The skin form of mastocytosis is mainly occurs in children. The article contains the current data on etiology, pathogenesis, classification, clinical forms, diagnosis, prophylactics and mastocytosis treatment at children.

Keywords

• мастоцитоз
• тучные клетки
• генотип
• с-kit
• мутации
• mastocytosis
• mast cells
• genotype
• c-kit
• mutations