Neuroendocrine tumors of the colon: an analysis of the literature and own experience

Abstract

Neuroendocrine tumors (NET) of the colon and rectum are rare diseases. In the treatment of patients with these rare diseases one should follow special standards which are differed from the standards of adenocarcinoma treatment. This article has analyzed the modern national literature, as well as our own experience in the treatment of 9 patients with NET of the colon in the period of 2007 to 2015. Average age - 60±14.6 years. Only NET of the rectum was identified at the first stage of the cancer. Endoscopic surgery was performed in 3 patients: two patients underwent endoscopic removal of the tumor and one - transanal endoscopic microsurgery associated with full-thickness resection of the rectum. Right-sided hemicolectomy was performed in 3 patients and anterior resection of the rectum (ARR) - in 1 patient. All operations were performed using standard oncology protocol associated with D2 lymph node dissection. We estimated the long-term outcomes of patients’ treatment. We analyzed the proposed by European colleagues algorithm of the treatment tactics in patients with neuroendocrine tumors of the colon, which in our point of view could be useful in medical practice of Russian doctors.

Keywords

• neuroendocrine tumors
• colon cancer
• rectal cancer
• surgery
• transanal surgery