Domestically Acquired NDM-1–Producing Pseudomonas aeruginosa, Southern California, USA, 2023

Abstract

We describe a case of New Delhi metallo-β-lactamase 1–producing carbapenem-resistant Pseudomonas aeruginosa (CRPA) in a transplant patient with multiple hospitalizations in California, USA. Whole-genome sequencing revealed the isolate was genetically distinctive, despite ≈95% similarity to other global strains. The patient’s lack of international travel suggests this CRPA was acquired domestically.

Keywords

• Pseudomonas aeruginosa
• bacteria
• antimicrobial resistance
• healthcare-associated infections
• California
• United States