THE EFFECT OF ANTIBIOTIC THERAPY ON THE INTESTINAL MICROBIOTA IN CHILDREN

Abstract

The article shows the main factors that have an effect on the intestinal microbiota. Most of the focus is on the slow recovery of Bifidobacterium population after antibiotic therapy with traditional azithromycin. The authors present the results of an open comparative study in children with rhinosinusitis to evaluate the efficacy and safety of traditional azithromycin and azithromycin with lactulose that is equivalent in antimicrobial activity, but superior in the safety profile, maintaining intestinal microflora balance and reducing the risk of antibiotic-associated diarrhea.

Keywords

• microbiota
• rhinosinusitis
• antibacterial therapy
• azithromycin with lactulose