Vitamin C protects against chronic social isolation stress-induced weight gain and depressive-like behavior in adult male rats

Abstract

Objective. Considering the importance of ghrelin in stress-induced hyperphagia and a role of antioxidants in decreasing body weight, in the present study, the effect of vitamin C (VitC) on ghrelin secretion and food intake following chronic social isolation (CIS) was evaluated in rats.

Keywords

• ghrelin
• vitamin c
• food intake
• chronic isolation stress
• depression-like behavior