Nature Communications (Mar 2020)

Identification of region-specific astrocyte subtypes at single cell resolution

  • Mykhailo Y. Batiuk,
  • Araks Martirosyan,
  • Jérôme Wahis,
  • Filip de Vin,
  • Catherine Marneffe,
  • Carola Kusserow,
  • Jordan Koeppen,
  • João Filipe Viana,
  • João Filipe Oliveira,
  • Thierry Voet,
  • Chris P. Ponting,
  • T. Grant Belgard,
  • Matthew G. Holt

DOI
https://doi.org/10.1038/s41467-019-14198-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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Astrocytes are a major cell type in the central nervous system. Using single cell transcriptome sequencing, the authors identify multiple astrocyte subtypes in the adult mouse CNS, which map to distinct spatial locations and show correlations to cell morphology and physiology.