Communications Biology (Jul 2022)

Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing

  • Silvia Rodriguez-Rozada,
  • Jonas Wietek,
  • Federico Tenedini,
  • Kathrin Sauter,
  • Neena Dhiman,
  • Peter Hegemann,
  • Peter Soba,
  • J. Simon Wiegert

DOI
https://doi.org/10.1038/s42003-022-03636-x
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 15

Abstract

Read online

Aion is an anion-conducting, bistable channelrhodopsin that enables long-term silencing of neuronal networks, as demonstrated in organotypic hippocampal cultures and Drosophila melanogaster larvae.