Nature Communications (Dec 2022)

Genomic analysis of sewage from 101 countries reveals global landscape of antimicrobial resistance

  • Patrick Munk,
  • Christian Brinch,
  • Frederik Duus Møller,
  • Thomas N. Petersen,
  • Rene S. Hendriksen,
  • Anne Mette Seyfarth,
  • Jette S. Kjeldgaard,
  • Christina Aaby Svendsen,
  • Bram van Bunnik,
  • Fanny Berglund,
  • Global Sewage Surveillance Consortium,
  • D. G. Joakim Larsson,
  • Marion Koopmans,
  • Mark Woolhouse,
  • Frank M. Aarestrup

DOI
https://doi.org/10.1038/s41467-022-34312-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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Understanding the emergence, evolution, and transmission of antibiotic resistance genes (ARGs) is essential to combat antimicrobial resistance. Here, Munk et al. analyse ARGs in hundreds of sewage samples from 101 countries and describe regional patterns, diverse genetic environments of common ARGs, and ARG-specific transmission patterns.