Case Reports in Women's Health (Apr 2022)

Stevens-Johnson syndrome with vulvar involvement: A case report and literature review

  • Jessie Hollingsworth,
  • Selena U. Park,
  • Veena Bhagavathi,
  • Ashlee Green,
  • Nancy Philips

DOI
https://doi.org/10.1016/j.crwh.2022.e00404
Journal volume & issue
Vol. 34
p. e00404

Abstract

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Stevens-Johnson syndrome is a rare, life-threatening mucocutaneous condition causing necrosis and detachment of the epidermis. Vulvovaginal involvement, seen in up to 70% of affected women, can lead to painful chronic conditions such as adenosis, hematocolpos, and chronic pelvic pain. To date, there is no consensus regarding the optimal treatment of vulvovaginal involvement. In this case report, one case of Stevens-Johnson syndrome with vulvar and vaginal involvement is described, and the treatment options for this rare condition are reviewed.

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