Non-Hodgkin Lymphoma Mimics Infected Total Knee Arthroplasty

Abstract

Lymphoma associated with total knee arthroplasty is a rare condition. We report a case of non-Hodgkin lymphoma mimicking an infected total knee arthroplasty. A 73-year-old woman who received left total knee replacement presented with fever and a discharging sinus over her left knee 12 weeks after surgery. The diagnosis of prosthetic joint infection was made and a two-stage revision arthroplasty planned. After implant removal and insertion of an antibiotic spacer in the first-stage operation, culture results of all intraoperative specimens were negative but the pathology report showed diffuse large B-cell lymphoma. She then received chemotherapy and a second-stage reconstruction operation. The wound healed uneventfully and she regained independent mobility. 中 文 摘 要: 與全膝關節置換相關的淋巴癌是罕見病症。我們報告一宗非何傑金氏淋巴癌模仿全膝關節置換感染的病例。一名73歲的女性患者在接受左膝全膝關節置換術12週後出現人工關節感染的病徵。臨床診斷為全膝關節置換感染，我們安排病人進行兩個階段全膝關節翻修置換術。我們為她進行第一階段清創手術後，膝關節組織樣本的病理報告顯示為淋巴癌。在接受了化療及第二階段全膝關節翻修置換術後，她的傷口順利癒合並能夠獨立步行。 Keywords: non-Hodgkin lymphoma, total knee arthroplasty