Journal of Pathology Informatics (Jan 2023)

Organizational preparedness for the use of large language models in pathology informatics

  • Steven N. Hart,
  • Noah G. Hoffman,
  • Peter Gershkovich,
  • Chancey Christenson,
  • David S. McClintock,
  • Lauren J. Miller,
  • Ronald Jackups,
  • Vahid Azimi,
  • Nicholas Spies,
  • Victor Brodsky

Journal volume & issue
Vol. 14
p. 100338

Abstract

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In this paper, we consider the current and potential role of the latest generation of Large Language Models (LLMs) in medical informatics, particularly within the realms of clinical and anatomic pathology. We aim to provide a thorough understanding of the considerations that arise when employing LLMs in healthcare settings, such as determining appropriate use cases and evaluating the advantages and limitations of these models.Furthermore, this paper will consider the infrastructural and organizational requirements necessary for the successful implementation and utilization of LLMs in healthcare environments. We will discuss the importance of addressing education, security, bias, and privacy concerns associated with LLMs in clinical informatics, as well as the need for a robust framework to overcome regulatory, compliance, and legal challenges.

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