Tactics for the correction of enteric microbiocenotic abnormalities in the combination therapy of patients with chronic liver diseases

Abstract

AIM: To evaluate the efficacy of the symbiotic Linex used in the combination therapy of liver cirrhosis (LC)/MATERIAL AND METHODS: Seventy-four patients with LC, including 44 who received additionally the symbiotic Linex and 30 who had conventional therapy, were examined. All the patients underwent clinical and biochemical blood tests, abdominal ultrasonography, fecal test for bacteria, gas chromatography-mass spectrometry of the blood composition of microbial markers, number connecting test, and quality-of-life assessment (SF-36)/RESULTS: The symbiotic-treated patients showed a significant improvement in biochemical parameters (decreases in transaminase activities, bilirubin levels, hepatic protein-synthetic function - there were elevations in the concentrations of total protein from 74.0±0.50 to 78.1±0.80 g/l (p

Keywords

• liver cirrhosis
• dysbiosis
• linex
• symbiotics