Diabetes, Metabolic Syndrome and Obesity (May 2021)
Prevalence and Risk Factors of Type 2 Diabetes and Prediabetes Among 53,288 Middle-Aged and Elderly Adults in China: A Cross-Sectional Study
Abstract
Mengdi Xia,1,* Kaixiang Liu,2,* Jie Feng,1 Zaiqiong Zheng,1 Xisheng Xie1 1Department of Nephrology, The Second Clinical Medical Institution of North Sichuan Medical College (Nanchong Central Hospital) and Nanchong Key Laboratory of Basic Science & Clinical Research on Chronic Kidney Disease, Nanchong, Sichuan, People’s Republic of China; 2Department of Nephrology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xisheng XieDepartment of Nephrology, The Second Clinical Medical Institution of North Sichuan Medical College (Nanchong Central Hospital), South Renmin Road 97, Shunqing District, Nanchong, Sichuan Province, 637000, People’s Republic of ChinaTel +86 158 8170 0265Email [email protected]: Diabetes is a metabolic disorder that causes a heavy burden on healthcare systems worldwide. The aim of this study was to determine the prevalence of type 2 diabetes and prediabetes and its associated factors among eight communities in Nanchong, China.Methods: This was an observational cross-sectional study conducted throughout eight communities in Nanchong, China. The participants were 53,288 individuals aged 45 years or older. The participants’ characteristics, comorbidities, health behaviors, family history, and dietary intake were assessed. Multinomial logistic regression models were fitted to identify factors associated with type 2 diabetes and prediabetes.Results: The prevalence of diabetes and prediabetes was 13.9% (95% confidence interval [CI], 13.6– 14.2) and 3.1% (95% CI, 2.9– 3.2) of the population, respectively. After adjusting for other risk factors, advanced age, overweight, obesity, abdominal obesity, comorbidities, smoking, a family history of diabetes, and Chinese cooking vegetable intake were associated with an increased risk of type 2 diabetes and prediabetes.Conclusion: The prevalence of type 2 diabetes in the Chinese population is rising compared with data from the past. The risk factors of type 2 diabetes and prediabetes identified in this study will aid the identification of individuals at a high-risk of diabetes and the implementation of effective health promotion programs and campaigns.Clinical Trial Registry Number: ChiCTR-HOC-17013200.Keywords: cross-sectional study, diabetes, prevalence, risk factors
