Dendritic cells and cytokines in skin in atopic dermatitis

Abstract

To study CD1a+ Langerhans cells and their extensions in epidermis and values of IL-4, IL-10, IL-17 and IFN-g in cell-free skin exudate there have been examined 40 patients of atopic dermatitis depending on phase pathological process. There have been found an increase in both CD1a+ dendritic extensions in medium layer of the epidermis and IL-4 and IL-10 in skin exudates. IFN-g exudate’s value has been decreased.

Keywords

• атопический дерматит
• дендритные клетки
• клетки лангерганса
• цитокины
• кожное окно