Hipofosforemia precoz en recién nacidos de riesgo. Frecuencia y magnitud

Abstract

Resumen: Objetivo: Conocer la frecuencia y la magnitud de la hipofosforemia neonatal ( 32 semanas con peso 32 weeks with weight < P10. Phase 2: 12 (16.4%) of 73 patients had a diagnosis of hypophosphataemia, with <2 mg/dL in 5 (6.8%). Eight (75%) of those with hypophosphataemia had IUGR, and 4 (25%) weighed < 1,000 g. Five cases had associated hypokalaemia, and three hypercalcaemia. Phase 3: 9 (45%) of 20 patients had hypophosphataemia, all of them < 1,000 g or < 1,200 g and weight percentile < 10. Thirty-three percent of samples on days 1, 3, and 7 showed hypophosphataemia, four of them < 2 mg/dL. There was mild hypokalaemia in 5 (55%), and mild hypercalcaemia in 2 (22%) cases. Hypophosphataemia was associated with lower enteral nutrition and higher parenteral amino acid intake in the early days of life. Conclusions: Hypophosphataemia is common, and can be severe, in the first week of life in premature infants < 1,000 grams, and newborns < 1,200 g with foetal malnutrition and receiving amino acids in early parenteral nutrition.

Keywords

• Hypophosphataemia
• Parenteral nutrition
• Prematurity
• Hypercalcaemia
• Hypokalaemia
• Newborn