Viruses (Apr 2023)
Isolation of Flaviviruses and Alphaviruses with Encephalitogenic Potential Diagnosed by Evandro Chagas Institute (Pará, Brazil) in the Period of 1954–2022: Six Decades of Discoveries
- Ana Lucia Monteiro Wanzeller,
- Fabio Silva da Silva,
- Leonardo Henrique Almeida Hernández,
- Landerson Junior Leopoldino Barros,
- Maria Nazaré Oliveira Freitas,
- Maissa Maia Santos,
- Ercília de Jesus Gonçalves,
- Jamilla Augusta Sousa Pantoja,
- Creuza de Sousa Lima,
- Maxwell Furtado Lima,
- Luiz Roberto Oliveira Costa,
- Liliane Leal das Chagas,
- Iveraldo Ferreira Silva,
- Tania Cristina Alves da Silveira da Cunha,
- Bruna Lais Sena do Nascimento,
- Helena Baldez Vasconcelos,
- Elizabeth Salbe Travassos da Rosa,
- Sueli Guerreiro Rodrigues,
- Raimunda do Socorro da Silva Azevedo,
- Lívia Carício Martins,
- Lívia Medeiros Neves Casseb,
- Jannifer Oliveira Chiang,
- Joaquim Pinto Nunes Neto,
- Ana Cecília Ribeiro Cruz,
- Valéria Lima Carvalho,
- Pedro Fernando da Costa Vasconcelos,
- Eliana Vieira Pinto da Silva
Affiliations
- Ana Lucia Monteiro Wanzeller
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Fabio Silva da Silva
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Leonardo Henrique Almeida Hernández
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Landerson Junior Leopoldino Barros
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Maria Nazaré Oliveira Freitas
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Maissa Maia Santos
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Ercília de Jesus Gonçalves
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Jamilla Augusta Sousa Pantoja
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Creuza de Sousa Lima
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Maxwell Furtado Lima
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Luiz Roberto Oliveira Costa
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Liliane Leal das Chagas
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Iveraldo Ferreira Silva
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Tania Cristina Alves da Silveira da Cunha
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Bruna Lais Sena do Nascimento
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Helena Baldez Vasconcelos
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Elizabeth Salbe Travassos da Rosa
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Sueli Guerreiro Rodrigues
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Raimunda do Socorro da Silva Azevedo
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Lívia Carício Martins
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Lívia Medeiros Neves Casseb
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Jannifer Oliveira Chiang
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Joaquim Pinto Nunes Neto
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Ana Cecília Ribeiro Cruz
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Valéria Lima Carvalho
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Pedro Fernando da Costa Vasconcelos
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- Eliana Vieira Pinto da Silva
- Viral Isolation Laboratory, Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute, Secretariat of Health and Environment Surveillance, Ministry of Health, Ananindeua 67030-000, Brazil
- DOI
- https://doi.org/10.3390/v15040935
- Journal volume & issue
-
Vol. 15,
no. 4
p. 935
Abstract
Viruses with encephalitogenic potential can cause neurological conditions of clinical and epidemiological importance, such as Saint Louis encephalitis virus, Venezuelan equine encephalitis virus, Eastern equine encephalitis virus, Western equine encephalitis virus, Dengue virus, Zika virus, Chikungunya virus, Mayaro virus and West Nile virus. The objective of the present study was to determine the number of arboviruses with neuroinvasive potential isolated in Brazil that corresponds to the collection of viral samples belonging to the Department of Arbovirology and Hemorrhagic Fevers, Evandro Chagas Institute (SAARB/IEC) of the Laboratory Network of National Reference for Arbovirus Diagnosis from 1954 to 2022. In the analyzed period, a total of 1,347 arbovirus samples with encephalitogenic potential were isolated from mice; 5,065 human samples were isolated exclusively by cell culture; and 676 viruses were isolated from mosquitoes. The emergence of new arboviruses may be responsible for diseases still unknown to humans, making the Amazon region a hotspot for infectious diseases due to its fauna and flora species characteristics. The detection of circulating arboviruses with the potential to cause neuroinvasive diseases is constant, which justifies the continuation of active epidemiological surveillance work that offers adequate support to the public health system regarding the virological diagnosis of circulating arboviruses in Brazil.
Keywords
