Serial assessment of multimodality imaging in anti-leucine-rich glioma-inactivated 1 antibody encephalitis: A case report

Takafumi Wada; Hitoshi Mori; Katsuro Shindo

eNeurologicalSci (Dec 2022)

Serial assessment of multimodality imaging in anti-leucine-rich glioma-inactivated 1 antibody encephalitis: A case report

Takafumi Wada,
Hitoshi Mori,
Katsuro Shindo

Affiliations

Takafumi Wada: Department of Neurology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki/Okayama, 710-8602, Japan
Hitoshi Mori: Department of Neurology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki/Okayama, 710-8602, Japan
Katsuro Shindo: Corresponding author.; Department of Neurology, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki/Okayama, 710-8602, Japan

Journal volume & issue: Vol. 29
p. 100426

Abstract

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In autoimmune encephalitis, abnormalities of diffusion-weighted imaging (DWI), fluid-attenuated inversion recovery (FLAIR), arterial spin labeling (ASL) in magnetic resonance imaging (MRI), single-photon emission computed tomography (SPECT) and 18F-fluorodeoxyglucose-positron emission tomography (18F-FDG-PET) have been reported. However, there are few studies of long-term follow-up of imaging. We report a case of anti-leucine-rich glioma-inactivated 1 antibody encephalitis whose MRI (DWI, FLAIR and ASL), 99mTcHM-PAO SPECT (PAO-SPECT) and 18F-FDG-PET were evaluated through the clinical course. ASL, PAO-SPECT and 18F-FDG-PET consistently showed abnormalities in almost the same area. Serial assessment of these imaging modalities is useful in evaluating disease activity and efficacy of treatment.

Published in eNeurologicalSci

ISSN: 2405-6502 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system
Website: https://www.journals.elsevier.com/eneurologicalsci/

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