Journal of Clinical Rheumatology and Immunology (Jul 2024)

AMPAR Encephalitis and Myasthenia Gravis in Systemic Lupus Erythematosus

  • Lay Hock Cheok,
  • Pei Chiek Teh,
  • Liu Hong Eow,
  • Wan Chee Goh,
  • Mohd Noor Nadiah,
  • Mohd Asmah,
  • Suk Chyn Gun

DOI
https://doi.org/10.1142/S2661341724720027
Journal volume & issue
Vol. 24, no. 01
pp. 48 – 52

Abstract

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A 38-year-old lady was diagnosed with systemic lupus erythematosus (SLE) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR) autoimmune encephalitis, fulfilling both classification criteria during her index admission. She was subsequently diagnosed with seropositive myasthenia gravis (MG) with a typical clinical presentation. Her SLE and AMPAR encephalitis were successfully treated with immunosuppressive therapy. Her MG responded well to anti-cholinesterase inhibitors. We report a distinctive case with the association of three rare autoimmune diseases in an individual.

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