PLoS ONE (Jan 2021)

Clinical characteristics and outcomes of patients with Corona Virus Disease 2019 (COVID-19) at Mercy Health Hospitals, Toledo, Ohio.

  • Muhammad Shayan Khan,
  • Ratika Dogra,
  • Leela K V Miriyala,
  • F N U Salman,
  • Rizwan Ishtiaq,
  • Dilnoor K Patti,
  • Aakash Kumar,
  • Gaurav Sandho,
  • Karim Jacob,
  • Kritika Luthra,
  • Ravina Sharma,
  • Rekha Ravikumar,
  • Dharmakaruna Edara,
  • Shanti Pittampalli,
  • Divya Sood,
  • Vinod Khatri,
  • Vijay Mahajan,
  • Salil Avasthi,
  • Arlette Auoad,
  • Srinivas Katragadda

DOI
https://doi.org/10.1371/journal.pone.0250400
Journal volume & issue
Vol. 16, no. 4
p. e0250400

Abstract

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ImportanceThe ongoing pandemic of the novel Corona Virus Disease 2019 (COVID-19) is an unprecedented challenge to global health, never experienced before.ObjectiveThis study aims to describe the clinical characteristics and outcomes of patients with COVID-19 admitted to Mercy Hospitals.Design and methodsRetrospective, observational cohort study designed to include every COVID-19 subject aged 18 years or older admitted to Mercy Saint (St) Vincent, Mercy St Charles, and Mercy St Anne's hospital in Toledo, Ohio from January 1, 2020 through June 15th, 2020. Primary Outcome Measure was mortality in the emergency department or as an in-patient.Results470 subjects including 224 males and 246 females met the inclusion criteria for the study. Subjects with the following characteristics had higher odds (OR) of death: Older age [OR 8.3 (95% CI 1.1-63.1, p = 0.04)] for subjects age 70 or more compared to subjects age 18-29); Hypertension [OR 3.6 (95% CI 1.6-7.8, p = 0.001)]; Diabetes [OR 3.1 (95% CI 1.7-5.6, pConclusionAge and hypertension were associated with significant comorbidity and mortality in Covid-19 Positive patients. Furthermore, people who were older than 70, and had hypertension, diabetes, COPD, or CKD had higher odds of dying from the disease as compared to patients who hadn't. Subjects with hypertension also had significantly greater odds of other adverse outcomes.