Nature Communications (Apr 2019)

Defining the genetic and evolutionary architecture of alternative splicing in response to infection

  • Maxime Rotival,
  • Hélène Quach,
  • Lluis Quintana-Murci

DOI
https://doi.org/10.1038/s41467-019-09689-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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Genetic ancestry might influence immunological response to infection at different regulatory levels. Here, the authors use RNA-Seq to investigate the variability of alternative splicing patterns in resting and stimulated monocytes of African- and European-descent.