Immunohistochemical Aspects of Cell Death in Diabetic Nephropathy

Abstract

Introduction. Diabetes Mellitus causes ultrastructural changes triggered by partially clarified cellular mechanisms. Since cell death is an important mechanism in the appearance and progression of diabetic nephropathy, we studied alteration of several markers of apoptotic pathways signaling in renal tissue of diabetic or prediabetic patients.

Keywords

• diabetes
• cell death
• apoptosis
• immunohistochemistry
• caspases