Uma visão da química bioinorgânica medicinal Medicinal bioinorganic chemistry

Química Nova. 2007;30(8):2062-2067 DOI 10.1590/S0100-40422007000800045

 

Journal Homepage

Journal Title: Química Nova

ISSN: 0100-4042 (Print); 1678-7064 (Online)

Publisher: Sociedade Brasileira de Química

Society/Institution: Sociedade Brasileira de Química

LCC Subject Category: Science: Chemistry

Country of publisher: Brazil

Language of fulltext: Portuguese, Spanish; Castilian, English

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AUTHORS

Anna Maria Canavarro Benite
Sérgio de Paula Machado
Eliezer J. Barreiro

EDITORIAL INFORMATION

Peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 12 weeks

 

Abstract | Full Text

<abstract language="eng">Metals play a vital role in human and plant physiology and important research is directed towards exploring the interrelated mechanisms that govern their interactions with biomolecules. Bioinorganic medicinal chemistry studies the functions, processing, storage and applications of metal ions and their complexes in biological systems. This paper presents a brief discussion about on interactions of metals with biomolecules that determine their intracellular accumulation, where metal ions may fulfill essential functions in cellular metabolism or, in certain cases, exert toxic effects towards cells.