Tacrolimus-induced pure red cell aplasia in a postrenal transplant patient

Abstract

Acquired pure red cell aplasia (PRCA) is an uncommon cause of anemia in a postrenal transplant patient. Most of the times, it is secondary to parvovirus infection. It can also be seen with certain autoimmune diseases, pregnancy, lymphoproliferative disorders, nutritional deficiencies, or medicines. We present the case of a living-related postrenal transplant patient who developed PRCA associated with tacrolimus. The patient responded when switched over to cyclosporine in 2½ months.

Keywords

• Cyclosporine
• pure red cell aplasia
• renal transplantation
• tacrolimus