Einstein (São Paulo) (Jun 2011)

Multiple myeloma: five-year experience at a University Hospital

  • Juliana Todaro,
  • Jandey Bigonha,
  • Davimar Miranda Maciel Borducchi,
  • Leandro Luongo Matos,
  • Damila Cristina Trufelli,
  • Suzane Martines Alves de Sales,
  • Marina Rampazzo Del Valhe Shiroma,
  • Auro del Giglio

Journal volume & issue
Vol. 9, no. 2
pp. 145 – 150

Abstract

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Objective: To present a descriptive analysis of patients diagnosedwith multiple myeloma, correlating it with mortality. Methods: Aretrospective study that analyzed consecutive patients diagnosedwith multiple myeloma under follow-up at the Faculdade deMedicina do ABC from 2006 to 2010. Results: The median agewas 58.5 years. Anemia was observed upon diagnosis in 87%of patients, hypercalcemia in 38%, and creatinine levels higherthan 2 mg/dL in 19%. M protein was detected in 85.7%. Thefive-year survival rate was 74.6%. Multivariate analysis showedstatistical significance for Durie-Salmon staging (p = 0.037). TheInternational Staging System and immunoglobulin type did notcorrelate significantly with survival of the group. Conclusion: Thisset of cases from a tertiary public healthcare service reflect theapproach of multiple myeloma in a predominantly young populationwith advanced clinical staging, with results comparable to thoseof the literature.

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