Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection

Nan He; Sirisha Thippabhotla; Cuncong Zhong; Zachary Greenberg; Liang Xu; Ziyan Pessetto; Andrew K. Godwin; Yong Zeng; Mei He

doi:10.1038/s42003-022-03598-0

Communications Biology (Jul 2022)

Nano pom-poms prepared exosomes enable highly specific cancer biomarker detection

Nan He,
Sirisha Thippabhotla,
Cuncong Zhong,
Zachary Greenberg,
Liang Xu,
Ziyan Pessetto,
Andrew K. Godwin,
Yong Zeng,
Mei He

Affiliations

Nan He: Department of Chemical and Petroleum Engineering, Bioengineering Program, University of Kansas
Sirisha Thippabhotla: Department of Electrical Engineering and Computer Science, University of Kansas
Cuncong Zhong: Department of Electrical Engineering and Computer Science, University of Kansas
Zachary Greenberg: Department of Pharmaceutics, College of Pharmacy, University of Florida
Liang Xu: Department of Molecular Biosciences, University of Kansas
Ziyan Pessetto: Department of Pathology and Laboratory Medicine, University of Kansas Medical Center
Andrew K. Godwin: Department of Pathology and Laboratory Medicine, University of Kansas Medical Center
Yong Zeng: Department of Chemistry, University of Florida
Mei He: Department of Chemical and Petroleum Engineering, Bioengineering Program, University of Kansas

DOI: https://doi.org/10.1038/s42003-022-03598-0
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

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3D-structured nanographene immunomagnetic particles with flower pompoms morphology and photo-click chemistry are applied for specific marker-defined capture and release of exosomes from several types of biological fluids, identifying targetable cancer biomarkers.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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