Isomeric Replacement of a Single Aspartic Acid Induces a Marked Change in Protein Function: The Example of Ribonuclease A

• Hiroaki Sakaue,
• Tadatoshi Kinouchi,
• Norihiko Fujii,
• Takumi Takata,
• Noriko Fujii

Affiliations

Hiroaki Sakaue

Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto, Japan

Tadatoshi Kinouchi

Research Reactor Institute, Kyoto University, Kumatori-cho, Osaka, Japan

Norihiko Fujii

Radioisotope Research Center, Teikyo University, Itabashi-ku, Tokyo, Japan

Takumi Takata

Research Reactor Institute, Kyoto University, Kumatori-cho, Osaka, Japan

Noriko Fujii

Research Reactor Institute, Kyoto University, Kumatori-cho, Osaka, Japan