Antibacterial and Anticancer Activity of Bioactive Fraction of Syzygium cumini L. Seeds

Abstract

Syzygium cumini L. better known as Jamun belonging to the family Myrtaceae is identified to have antidiabetic, anti-inflammatory, anti-pyretic and anti-oxidant activities. Anticancer activity of S. cumini L. fruits has been demonstrated. However, anticancer activity of S. cumini seeds on various types of human cancers has not been explored much. The methanol fraction of ethanol extract from the seeds of S. cumini was found to have significant antibacterial activity. This bioactive fraction was further tested positive for its anticancer activity on various types of human cancer cell lines indicating its potency. Structural characterization of the bioactive fraction was achieved using analysis of high performance liquid chromatography, ultra violet and infra red spectrum.

Keywords

• Syzygium cumini L.
• antibacterial activity
• cytotoxic activity
• structural characterization