Abstract P-50: On the Features of X-Ray Laser Diffraction on Certain Elements of Macromolecular Structures

Abstract

The possibility of using free electron X-ray lasers for solving problems of structural biology in single particle experimental mode is discussed. In the first Born approximation analytical expressions for the amplitudes and intensities of X-ray diffraction on cylinders, balls, hemispheres and tori in various combinations and orientations are obtained. The characteristic diffraction patterns from these geometric bodies are analyzed. The modeling of elements of the secondary structure of biopolymers (for example, alpha-helices, characteristic DNA packs, some viruses, etc.) is discussed by a certain set of these geometric bodies with the corresponding parameters.

Keywords

• XFEL
• X-ray diffraction
• single particle
• Bessel and Lommel functions