Natural hosts and animal models for Rift Valley fever phlebovirus

Yuqing Xu; Yuqing Xu; Yuqing Xu; Xiao Wang; Xiao Wang; Lu Jiang; Lu Jiang; Yixuan Zhou; Yixuan Zhou; Yihan Liu; Yihan Liu; Fei Wang; Fei Wang; Leiliang Zhang; Leiliang Zhang; Leiliang Zhang

doi:10.3389/fvets.2023.1258172

Frontiers in Veterinary Science (Oct 2023)

Natural hosts and animal models for Rift Valley fever phlebovirus

Yuqing Xu,
Yuqing Xu,
Yuqing Xu,
Xiao Wang,
Xiao Wang,
Lu Jiang,
Lu Jiang,
Yixuan Zhou,
Yixuan Zhou,
Yihan Liu,
Yihan Liu,
Fei Wang,
Fei Wang,
Leiliang Zhang,
Leiliang Zhang,
Leiliang Zhang

Affiliations

Yuqing Xu: Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China
Yuqing Xu: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Yuqing Xu: Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
Xiao Wang: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Xiao Wang: Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
Lu Jiang: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Lu Jiang: Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
Yixuan Zhou: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Yixuan Zhou: Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
Yihan Liu: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Yihan Liu: Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
Fei Wang: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Fei Wang: School of Laboratory Animal and Shandong Laboratory Animal Center, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
Leiliang Zhang: Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, China
Leiliang Zhang: Medical Science and Technology Innovation Center, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China
Leiliang Zhang: Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China

DOI: https://doi.org/10.3389/fvets.2023.1258172
Journal volume & issue: Vol. 10

Abstract

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Rift Valley fever phlebovirus (RVFV) is a zoonotic mosquito-transmitted arbovirus, presenting a serious threat to humans and animals. Susceptible hosts are of great significance for the prevention of RVFV. Appropriate animal models are helpful to better understand the onset and development of diseases, as well as the control measures and vaccine research. This review focuses on the role of animal hosts in the maintenance of the virus, and summarizes the host range of RVFV. We list some common animal models in the process of RVFV research, which would provide some important insights into the prevention and treatment of RVFV, as well as the study of Rift Valley fever (RVF) pathogenesis and vaccines.

Published in Frontiers in Veterinary Science

ISSN: 2297-1769 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Agriculture: Animal culture: Veterinary medicine
Website: https://www.frontiersin.org/journals/veterinary-science

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