Nutritional neurology: Unraveling cellular mechanisms of natural supplements in brain health

Abstract

The consequence of appropriate food consumption and the corresponding amount of dietary nutrients on brain function is widely recognized. More and more studies are pointing to the importance of diet for alleviating neurological symptoms associated with a wide range of clinical disorders. The recently discovered implications of nutritional variables on modifications in mitochondrial dysfunction, epigenetic modification, and neurological inflammation represent important factors that play a crucial role in determining the effect of nutrition on Neuronal (health). This overview investigates the present state of evidence regarding the efficacy of various dietary interventions, such as dietary supplements and dietary restrictions, for in the context of managing disorders related to the brain. Particularly, it clearly state the consequences of these interventions on conditions such as Alzheimer's, Parkinson's, ischemic stroke, seizures, injury to the brain, amyotrophic lateral sclerosis (ALL), Huntington's syndrome, and multiple sclerosis (MS). Along with this, it is important to note that a variety of possible processes, such as metabolic regulation, epigenetic alteration, and the inflammation of neurons assume a pivotal function. in determining the impact of nutrition availability on the risk of neurologic conditions and treatment outcomes. Along with this, authors clearly state the innovative concept that dietary supplement intervention can modify interconnected processes of metabolism, epigenetics, and immunology, thereby addressing brain dysfunction. Concentrating on metabolic processes the study of the epigenetic-immunity network has the potential to provide a novel framework for addressing vulnerabilities in the field of neurology.

Keywords

• Reactive oxygen species
• Amyotrophic lateral sclerosis
• Jumonji domain (Jmjd3) ketogenic diet (KD)
• Agouti genes
• Brain-derived neurotrophic factor (BDNF)