1046 A long-acting and Beta-intensified IL-2 analog, HM16390, significantly alters tumors to an immune favorable environment to potentiate PD-1 blockade

• Sang Hyun Park,
• Jaehyuk Choi,
• Jinyoung Kim,
• Seongju Jeong,
• Yuyon Kim,
• Sungmin Bae,
• Daejin Kim,
• In Young Choi

Affiliations

Sang Hyun Park

Hanmi Pharm. Co., Ltd, Hwaseong-si, Gyeonggi-do, Republic of Korea

Jaehyuk Choi

Aff2 0000 0001 2299 3507grid.16753.36Robert H. Lurie Comprehensive Cancer Center of Northwestern University 645 N. Michigan Avenue, Suite 1006 60611 Chicago IL USA

Jinyoung Kim

Hanmi Pharm. Co., Ltd, Hwaseong-si, Gyeonggi-do, Republic of Korea

Seongju Jeong

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea (the Republic of)

Yuyon Kim

Hanmi Pharm. Co., Ltd, Hwaseong-si, Gyeonggi-do, Republic of Korea

Sungmin Bae

Hanmi Pharm. Co., Ltd, Hwaseong-si, Gyeonggi-do, Republic of Korea

Daejin Kim

Hanmi Pharm. Co., Ltd, Hwaseong-si, Gyeonggi-do, Republic of Korea

In Young Choi

Hanmi Pharm. Co., Ltd, Hwaseong-si, Gyeonggi-do, Republic of Korea