Innovative medicines for treatment of psoriatic arthritis

Abstract

The problem of effective treatment of psoriatic arthritis has not been solved yet. The search for new therapeutic options is very active in many directions. At the stage of clinical trials are drugs that block interleukin-17-a (secukinumab, ixekizumab, brodalumab), drugs that suppress interleukin-12 and interleukin-23 (ustekinumab). To modern means to ensure psoriatic arthritis include drugs that are inhibitors of small molecules orkinase pathways (apremilast, tofacitinib).

Keywords

• inhibitors of interleukin-17-a, inhibitors of interleukin-12, inhibitors of interleukin-23
• Janus-kinase inhibitor
• psoriatic arthritis