Hematology, Transfusion and Cell Therapy (May 2024)

A Case of Multiple Myeloma with Atypical Cutaneous Presentation Treated by Daratumumab + CYBORG

  • Bengisu Ece DUMAN,
  • Candas MUMCU,
  • Berra Nur ISCI,
  • Emre BAL,
  • Meryem SENER,
  • Hande Yanar,
  • Arbil ACIKALIN,
  • Birol GUVENC

Journal volume & issue
Vol. 46
pp. 9 – 10

Abstract

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This case report illustrates the unconventional progression of multiple myeloma (MM) in a 57-year-old male, primarily highlighted by a cutaneous manifestation on the right cheek malar region, indicative of disease recurrence. Initially diagnosed following back pain and dyspnea, the patient's journey took a distinctive path from standard multiple myeloma treatments to the innovative application of daratumumab + CYBORG therapy. The biopsy from the lesion confirmed the recurrence of plasma cell neoplasia, leading to the adoption of daratumumab + CYBORG therapy. This innovative treatment strategy underscores the evolving landscape of MM management, particularly in cases presenting with atypical symptoms such as cutaneous involvement. The implementation of daratumumab + CYBORG therapy in this context not only highlights its potential as a significant advancement in MM treatment.