Вопросы современной педиатрии (Jan 2011)

EFFICACY OF ETANERCEPT IN CHILD WITH SEVERE POLYARTICULAR TYPE OF JUVENILE RHEUMATOID ARTHRITIS

  • T.M. Bzarova,
  • Ye.I. Alexeeva,
  • S.I. Valieva,
  • N.A. Tsurikova,
  • E.G. Chistyakova,
  • K.B. Isaeva,
  • R.V. Denisova,
  • T.V. Sleptsova,
  • E.V. Mitenko

Journal volume & issue
Vol. 10, no. 2
pp. 184 – 192

Abstract

Read online

The article presents a case report of severe and prolonged polyarticular rheumatoid arthritis resistant to the treatment with classic immunosuppressive agents, nonsteroidal anti-inflammatory drugs and corticosteroids. Authors describe successful treatment with soluble receptors to TNF _ — etanercept 0.4 mg for 1 kg of body weight during 36 weeks. Pain and exudative inflammation in joints lessened and the range of motions in joints increased in 4 weeks after the beginning of treatment. 9 months of treatment significantly increased the quality of life of a child and parents.Key words: children, juvenile rheumatoid arthritis, etanercept.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2011; 10 (2): 184–192)