Nature Communications (Jun 2021)
Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus
- Andrea Doni,
- Raffaella Parente,
- Ilaria Laface,
- Elena Magrini,
- Cristina Cunha,
- Federico Simone Colombo,
- João F. Lacerda,
- António Campos,
- Sarah N. Mapelli,
- Francesca Petroni,
- Rémi Porte,
- Tilo Schorn,
- Antonio Inforzato,
- Toine Mercier,
- Katrien Lagrou,
- Johan Maertens,
- John D. Lambris,
- Barbara Bottazzi,
- Cecilia Garlanda,
- Marina Botto,
- Agostinho Carvalho,
- Alberto Mantovani
Affiliations
- Andrea Doni
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Raffaella Parente
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Ilaria Laface
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Elena Magrini
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Cristina Cunha
- Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho
- Federico Simone Colombo
- IRCCS Humanitas Research Hospital, via Manzoni 56
- João F. Lacerda
- Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa
- António Campos
- Serviço de Transplantação de Medula Óssea (STMO), Instituto Português de Oncologia do Porto
- Sarah N. Mapelli
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Francesca Petroni
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Rémi Porte
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Tilo Schorn
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Antonio Inforzato
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Toine Mercier
- Department of Hematology, University Hospitals Leuven
- Katrien Lagrou
- Department of Microbiology, Immunology and Transplantation, KU Leuven
- Johan Maertens
- Department of Hematology, University Hospitals Leuven
- John D. Lambris
- Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania
- Barbara Bottazzi
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Cecilia Garlanda
- IRCCS Humanitas Research Hospital, via Manzoni 56
- Marina Botto
- Department of Immunology and Inflammation, Imperial College London
- Agostinho Carvalho
- Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho
- Alberto Mantovani
- IRCCS Humanitas Research Hospital, via Manzoni 56
- DOI
- https://doi.org/10.1038/s41467-021-24021-y
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 15
Abstract
Serum Amyloid P is a humoral component with established roles in the response to bacterial infection and regulation of tissue remodeling. Here the authors provide evidence to a further crucial role of serum amyloid P in the context of fungal pathogen Aspergillus fumigatus.