Nature Communications (Jun 2021)

Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

  • Andrea Doni,
  • Raffaella Parente,
  • Ilaria Laface,
  • Elena Magrini,
  • Cristina Cunha,
  • Federico Simone Colombo,
  • João F. Lacerda,
  • António Campos,
  • Sarah N. Mapelli,
  • Francesca Petroni,
  • Rémi Porte,
  • Tilo Schorn,
  • Antonio Inforzato,
  • Toine Mercier,
  • Katrien Lagrou,
  • Johan Maertens,
  • John D. Lambris,
  • Barbara Bottazzi,
  • Cecilia Garlanda,
  • Marina Botto,
  • Agostinho Carvalho,
  • Alberto Mantovani

DOI
https://doi.org/10.1038/s41467-021-24021-y
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

Read online

Serum Amyloid P is a humoral component with established roles in the response to bacterial infection and regulation of tissue remodeling. Here the authors provide evidence to a further crucial role of serum amyloid P in the context of fungal pathogen Aspergillus fumigatus.