Intracycle power distribution in a heterogeneous multi-compartmental mathematical model: possible links to strain and VILI

Philip S. Crooke; Luciano Gattinoni; Michael Michalik; John J. Marini

doi:10.1186/s40635-022-00447-6

Intensive Care Medicine Experimental (Jun 2022)

Intracycle power distribution in a heterogeneous multi-compartmental mathematical model: possible links to strain and VILI

Philip S. Crooke,
Luciano Gattinoni,
Michael Michalik,
John J. Marini

Affiliations

Philip S. Crooke: Department of Mathematics, Vanderbilt University
Luciano Gattinoni: Department of Anesthesiology and Intensive Care, Gottingen University
Michael Michalik: Department of Medicine, University of Minnesota
John J. Marini: Pulmonary and Critical Care Medicine, Regions Hospital, University of Minnesota

DOI: https://doi.org/10.1186/s40635-022-00447-6
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 14

Abstract

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Take home message Potentially damaging tidal energy and power distribute asymmetrically within the heterogeneous environment of the acutely injured lung. Clinician-selected flow profiles not only influence the timing of power delivery, but also spatially distribute the attendant strains of expansion.

Published in Intensive Care Medicine Experimental

ISSN: 2197-425X (Online)
Publisher: SpringerOpen
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Medical emergencies. Critical care. Intensive care. First aid
Website: https://icm-experimental.springeropen.com/

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Abstract

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