Comprehensive evaluations of coronavirus disease 2019 survivors regarding immunity, laboratory and computed tomography change

Abstract

Background Long coronavirus disease is an incapacitating disease that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 infections. At least 65 million persons global are estimated to have long COVID, with situations increasing daily. Patients and methods This is a prospective cohort study done on COVID-19 survivors’ proved by computed tomography (CT) or RCR testing who registered for follow-up at post-COVID Clinic at Family Medicine Department in Zagazig University Hospital through systematic random sampling technique. Survivors followed-up for 6 months by three visits. Results Total 137 adult patients with COVID-19 were included in this study. Mean age of the studied group 42.01 ± 8.28 years where most of them were females (78.1%). As regards inflammatory marker C-reactive protein, erythrocyte sedimentation rate (ESR) and D-dimer were slightly elevated and improving in the subsequent visits but complete blood picture, liver functions, kidney function, cardiac enzymes result through follow-up visits were in normal range. As regards CT change (72.3%) demonstrated abnormal CT in first visit and became (20.5%) at follow-up visit. As regards serology results, 100% demonstrated positive serology in first measurement and 12.5% turned negative in follow-up measurement after 3 months. Conclusion Small percent of COVID-19 patients present with some abnormalities, but after follow-up period we observed overall improvement in all parameters.

Keywords

• coronavirus disease 2019; computed tomography; immunity; lab; acute respiratory syndrome coronavirus 2