Acta Biomedica Scientifica (Feb 2013)
Clinical-microbiological characteristics of stationary urinary tract infections in capable people in conditions of north
Abstract
Urgency of the research was determined by insufficiency of information in modern literature about microbiological structure antibiotic sensitivity of main pathogens of urinary tract infection among capable people in conditions of hospital. The aim. of the research was to increase effectiveness of antibiotic therapy of stationary infections of urinary tract in conditions of north. The results of stationary examination of 1109 capable patients (males and. females) with infections of urinary tract from 1998 to 2009 years were studied. Data of microbiological examination is based on 700 bacteriological urine analyses. Antibiotic sensitivity of uropathogens was determined by disc-diffuse method. Structure of stationary infections of urinary tract in groups of patients of one sex was quite equal, but at the same time there are significant differences between groups of males and. females. Lately infections of urinary tract caused by intrahospital pathogens that are non-sensitive to common antibiotics (Proteus, KIebsieIIa and. Pseudomonas родов) started to be revealed, in patients arriving from other hospitals. It demands using reserve antibiotics. This underscores urgency of monitoring of uropathogens spectrum, and. their antibiotic-sensitivity for each hospital that has respective possibiIities. It was reveaIed. that chronic pyelonephritis with concomitant urolithiasis is the main nosoform in capable peopIe in conditions of north, in the structure of stationary infections of urinary tract. Acute and uncomplicated chronic pyeIonephritis and. aIso acute and. chronic cystitis more than twice prevaiI among femaIes in comparison, with males. The most important pathogens of stationary infections of urinary tract are: S. epidermidis, S. saprophyticus S. aureus for men; E. coIi, S. еpidermidis S. saprophyticus and. S. aureus for women at uncompIicated infections of urinary tract and. E. coli, S. saprophyticus, S. epidermidis for women at compIicated infections of urinary tract. Main uropathogens in researched, contingent had. higher sensitivity in vitro for gentamycin ofIoxacin, and Iower sensitivity — for cefotaxime, ceftriaxone and. ciprofloxacin. The most of resistant cuItures for antibacterial preparations that are the most frequently used for the treatment of infections of urinary tract is among E. coli, the Ieast part — among S. aureus.
