The myxocoumarins A and B from Stigmatella aurantiaca strain MYX-030

Abstract

The myxobacterial strain Stigmatella aurantiaca MYX-030 was selected as promising source for the discovery of new biologically active natural products by our screening methodology. The isolation, structure elucidation and initial biological evaluation of the myxocoumarins derived from this strain are described in this work. These compounds comprise an unusual structural framework and exhibit remarkable antifungal properties.

Keywords

• antifungal activity
• myxobacteria
• natural products
• Stigmatella aurantiaca
• structure elucidation