Frontiers in Pediatrics (Oct 2022)

Case Report: Recurrent pericardial tamponade in a child with COVID-19

  • Ádám Győri,
  • Tamás Decsi,
  • József Stankovics,
  • Zoltán Nyul,
  • Mária Környei,
  • György Masszi,
  • Evelin Leibinger,
  • Bernadett Mosdósi

DOI
https://doi.org/10.3389/fped.2022.1026349
Journal volume & issue
Vol. 10

Abstract

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BackgroundPericarditis is rare in Coronavirus disease 2019 (Covid-19) infection and only a few cases were reported in children.Case presentationWe present the case of a 15-year-old boy with symptoms of high fever and worsening chest pain during COVID-19 infection. Chest computer tomography (CT) and echocardiography confirmed pericardial tamponade requiring urgent drainage. Despite antiviral drug treatment, after 18 days severe attack developed requiring repeated pericardiocentesis. High dose ibuprofen, colchicin and the interleukin-1 antagonist, anakinra were given. Clinical symptoms and laboratory parameters improved after seven days of treatment. Autoinflammatory diseases were also suspected in the background the severe pericarditis, but genetic analysis ruled out any mutations.ConclusionPericarditis associated with COVID-19 infection may present in the acute phase or later as MIS-C. Though pericardial tamponade related to ongoing Covid-19 infection is rare in children, even biological treatment with interleukin-1 antagonist may be needed to control the inflammation.

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