Nature Communications (Oct 2017)

A long-range cis-regulatory element for class I odorant receptor genes

  • Tetsuo Iwata,
  • Yoshihito Niimura,
  • Chizuru Kobayashi,
  • Daichi Shirakawa,
  • Hikoyu Suzuki,
  • Takayuki Enomoto,
  • Kazushige Touhara,
  • Yoshihiro Yoshihara,
  • Junji Hirota

DOI
https://doi.org/10.1038/s41467-017-00870-4
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 12

Abstract

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“Each olfactory sensory neuron expresses a single odorant receptor gene from either class I or class II genes. Here, the authors identify an enhancer for mouse class I genes, that is highly conserved, and regulates most class I genes expression by acting over ~ 3 megabases within the whole cluster.”