1135 A novel self-assembling vaccine, VTX-067, targeting E6/E7 proteins of human papilloma virus induces T cell immune responses and inhibits HPV E6/E7 expressing tumor growth in a C57/B6 mouse model

• Mark C Poznansky,
• Paul Korner,
• Yohannes Gemechu,
• Sonia Mukherjee,
• Jeffrey A Gelfand,
• Timothy A Brauns,
• Ann E Sluder,
• Pierre R Leblanc,
• George Steinfels,
• Ishan Kapila,
• Zachary Shriver,
• Patrick M Reeves

Affiliations

Mark C Poznansky

Aff1 grid.32224.350000000403869924Massachusetts General Hospital Boston MA USA

Paul Korner

3Voltron Therapeutics, Inc, New York, NY, USA

Yohannes Gemechu

1Massachusetts General Hospital, Charlestown, MA, USA

Sonia Mukherjee

2Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

Jeffrey A Gelfand

2Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

Timothy A Brauns

2Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

Ann E Sluder

2Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

Pierre R Leblanc

2Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA

George Steinfels

3Voltron Therapeutics, Inc, New York, NY, USA

Ishan Kapila

3Voltron Therapeutics, Inc, New York, NY, USA

Zachary Shriver

3Voltron Therapeutics, Inc, New York, NY, USA

Patrick M Reeves

2Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA