Four-Step Synthesis of 3-Allyl-2-(allyloxy)-5-bromoaniline from 2-Allylphenol

Enrique B. Aparicio; Stephen R. Isbel; Alejandro Bugarin

doi:10.3390/M1773

Molbank (Feb 2024)

Four-Step Synthesis of 3-Allyl-2-(allyloxy)-5-bromoaniline from 2-Allylphenol

Enrique B. Aparicio,
Stephen R. Isbel,
Alejandro Bugarin

Affiliations

Enrique B. Aparicio: Department of Chemistry and Physics, Florida Gulf Coast University, 10501 FGCU Boulevard South, Fort Myers, FL 33965, USA
Stephen R. Isbel: Department of Chemistry and Physics, Florida Gulf Coast University, 10501 FGCU Boulevard South, Fort Myers, FL 33965, USA
Alejandro Bugarin: Department of Chemistry and Physics, Florida Gulf Coast University, 10501 FGCU Boulevard South, Fort Myers, FL 33965, USA

DOI: https://doi.org/10.3390/M1773
Journal volume & issue: Vol. 2024, no. 1
p. M1773

Abstract

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This communication reports a four-step protocol to produce 3-allyl-2-(allyloxy)-5-bromoaniline 5 from commercially available 2-allylphenol. The synthetic steps used were nitration, selective bromination, allylation, and reduction of the nitro group.

Published in Molbank

ISSN: 1422-8599 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Inorganic chemistry
Website: https://www.mdpi.com/journal/molbank

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