Advanced Modeling and Simulation in Engineering Sciences (Sep 2021)

Coupling reduced-order blood flow and cardiac models through energy-consistent strategies: modeling and discretization

  • Jessica Manganotti,
  • Federica Caforio,
  • François Kimmig,
  • Philippe Moireau,
  • Sebastien Imperiale

DOI
https://doi.org/10.1186/s40323-021-00206-4
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 37

Abstract

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Abstract In this work we provide a novel energy-consistent formulation for the classical 1D formulation of blood flow in an arterial segment. The resulting reformulation is shown to be suitable for the coupling with a lumped (0D) model of the heart that incorporates a reduced formulation of the actin-myosin interaction. The coupling being consistent with energy balances, we provide a complete heart-circulation model compatible with thermodynamics hence stable numerically and informative physiologically. These latter two properties are verified by numerical experiments.

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