Health and Quality of Life Outcomes (Feb 2019)

Inflammation and quality of life in later life: findings from the health, well-being and aging study (SABE)

  • Manuela de Almeida Roediger,
  • Maria de Fátima Nunes Marucci,
  • Etienne Larissa Duim,
  • Jair Lício Ferreira Santos,
  • Yeda Aparecida de Oliveira Duarte,
  • Cesar de Oliveira

DOI
https://doi.org/10.1186/s12955-019-1092-2
Journal volume & issue
Vol. 17, no. 1
pp. 1 – 7

Abstract

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Abstract Background Few studies have specifically investigated the inverse relationship between reduced quality of life in different domains and elevated C-reactive protein (CRP) serum levels in older adults. Therefore, this study investigates the cross-sectional association between quality of life and inflammation in older Brazilian adults. Methods Data were collected from 1255 participants from the third wave (2010) of the Brazilian Health, Well-being and Aging study (SABE), a community-based cohort study of aging. Inflammation was assessed using CRP serum levels and quality of life (QoL) was measured using the 12-item Short-Form Health Survey (SF-12) questionnaire. The covariates included age, sex, education level, financial sufficiency, number of non-communicable diseases, self-reported doctor diagnosed diseases, Activity of Daily Living (ADL) difficulties, Body Mass Index (BMI), and waist circumference. Results The fully adjusted models showed that older adults with low scores in the physical domain of the SF12 (OR 1.34, 95%CI 1.02;1.77) and high BMI values (> 30) (OR 2.05, 95%CI 1.50;2.81) were more likely to present high CRP serum levels. Conclusion Our findings suggest a significant association of lower scores in the physical domain of quality of life and the presence of obesity with high CRP serum levels.

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