Magnesium deficiency is an important factor in the etiopathogenesis of premenstrual syndrome (PMS) and the cause of complications in patients receiving menopausal hormone therapy (MHT).Materials and methods. The results of a meta-analysis of 8 clinical studies on the use of magnesium preparations in the form of organic salts for oral administration.Conclusions. PMS therapy includes the use of drugs, e.g. magnesium which is associated with a reduction in PMS symptoms: irritability, and emotional lability (5 studies, n=775, OR 0,24, 95% CI 0,20-0,29, p