mBio
(Oct 2021)
Differential Effects of Prostaglandin D
<sub>2</sub>
Signaling on Macrophages and Microglia in Murine Coronavirus Encephalomyelitis
Abhishek Kumar Verma,
Jian Zheng,
Matthias Mack,
Florent Ginhoux,
Stanley Perlman
Affiliations
Abhishek Kumar Verma
Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA
Jian Zheng
Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA
Matthias Mack
Department of Internal Medicine II, University Hospital Regensburg, Regensburg, Germany
Florent Ginhoux
Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Stanley Perlman
ORCiD
Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa, USA
DOI
https://doi.org/10.1128/mBio.01969-21
Journal volume & issue
Vol. 12,
no. 5
Abstract
Read online
Current understanding about the roles of microglia versus macrophages in viral encephalitis is limited. We previously showed that the signaling of a single prostaglandin, PGD 2
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