Mouse MRI shows brain areas relatively larger in males emerge before those larger in females

Lily R. Qiu; Darren J. Fernandes; Kamila U. Szulc-Lerch; Jun Dazai; Brian J. Nieman; Daniel H. Turnbull; Jane A. Foster; Mark R. Palmert; Jason P. Lerch

doi:10.1038/s41467-018-04921-2

Nature Communications (Jul 2018)

Mouse MRI shows brain areas relatively larger in males emerge before those larger in females

Lily R. Qiu,
Darren J. Fernandes,
Kamila U. Szulc-Lerch,
Jun Dazai,
Brian J. Nieman,
Daniel H. Turnbull,
Jane A. Foster,
Mark R. Palmert,
Jason P. Lerch

Affiliations

Lily R. Qiu: Institute of Medical Science, University of Toronto
Darren J. Fernandes: Mouse Imaging Centre, The Hospital for Sick Children
Kamila U. Szulc-Lerch: Mouse Imaging Centre, The Hospital for Sick Children
Jun Dazai: Mouse Imaging Centre, The Hospital for Sick Children
Brian J. Nieman: Mouse Imaging Centre, The Hospital for Sick Children
Daniel H. Turnbull: Skirball Institute of Biomolecular Medicine, New York University School of Medicine
Jane A. Foster: Department of Psychiatry & Behavioural Neurosciences, McMaster University
Mark R. Palmert: Institute of Medical Science, University of Toronto
Jason P. Lerch: Mouse Imaging Centre, The Hospital for Sick Children

DOI: https://doi.org/10.1038/s41467-018-04921-2
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 15

Abstract

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Sex differences occur in various aspects of neurodevelopment. Here the authors use manganese-enhanced MRI at nine different postnatal stages to detail the development of structural sex differences in the mouse brain.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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