Correlation Between HbA1c and Albuminuria in Type 2 Diabetes Mellitus

Abstract

In patients with type 2 diabetes mellitus (Type 2 DM), glycemic control plays an essential role in reducing macro- and microvascular complications. The earliest marker for diabetic nephropathy is the presence of albuminuria. Meanwhile, HbA1c has been recognized as a marker of glycemic control in the blood. This study aimed to identify the correlation between HbA1c and albuminuria in type 2 DM. This was a cross-sectional study involving 100 patients with type 2 DM aged 40–70 years visiting Dr. Soetomo Hospital, Surabaya, Indonesia. Secondary data from medical records of type 2 DM patients undergoing HbA1c and albuminuria examinations from January to December 2015 were used. The mean age of subjects was 55.4 ±8.7 years, with the majority (55%) being of female gender. The mean HbA1c concentration was 9.8±2.4%. Most subjects (83%) had an HbA1c level of ≥7 %. Albuminuria was found in the majority of the subjects (78%), where 33% of them had positive 1 albuminuria. The Spearman correlation test showed a positive strong significant correlation between HbA1c and albuminuria, with r=0.865 and p<0.001. Thus, it can be concluded that there is a significant correlation between HbA1c and albuminuria in type 2 DM.

Keywords

• albuminuria, diabetic nephropathy, hba1c, type 2 diabetes mellitus