Compassionate Use of Contezolid for the Treatment of Tuberculous Pleurisy in a Patient with a Leadless Pacemaker

Abstract

Yixin Kang,1,* Cheng Ge,2,* Huan Zhang,3 Saizhe Liu,4 Hongyang Guo,4 Junchang Cui1 1Department of Respiratory Diseases, the First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, 100853, People’s Republic of China; 2Department of Cardiology, the First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, 100853, People’s Republic of China; 3Center of Medicine Clinical Research, the First Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, 100853, People’s Republic of China; 4Department of Cardiology, the Sixth Medical Center, Chinese People’s Liberation Army General Hospital, Beijing, 100853, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hongyang Guo; Junchang Cui, The First Medical Center, Chinese People’s Liberation Army General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, People’s Republic of China, Email [email protected]; [email protected]: We report the case of an 87-year-old woman with tuberculous pleurisy. She developed adverse effects in the form of thrombocytopenia and gastrointestinal hemorrhage with isoniazid, and thrombocytopenia with linezolid. Her treatment was switched to contezolid plus cycloserine for a 4-week antibiotic duration, with a favorable outcome.Keywords: contezolid, tuberculous pleurisy

Keywords

• contezolid
• tuberculous pleurisy.